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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EOMES All Species: 20.91
Human Site: S141 Identified Species: 38.33
UniProt: O95936 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95936 NP_005433.2 686 72732 S141 Y S M D S L S S E R Y Y L Q S
Chimpanzee Pan troglodytes XP_001165803 690 73333 S145 Y S M D S L S S E R Y Y L Q S
Rhesus Macaque Macaca mulatta XP_001093085 737 80029 S174 Y S M D S L S S E R Y Y L P S
Dog Lupus familis XP_850738 688 72729 S143 Y S M D S L S S E R Y Y L Q S
Cat Felis silvestris
Mouse Mus musculus O54839 707 74783 S143 Y S M D S L S S E R Y Y L P S
Rat Rattus norvegicus XP_001061749 663 70857 D140 A T A R Y S M D S L S S E R Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514679 386 42515
Chicken Gallus gallus XP_426003 399 44936
Frog Xenopus laevis P79944 692 75925 D139 T S A P R Y L D G S L Q A A S
Zebra Danio Brachydanio rerio NP_571754 661 71990 S139 G Q T G S V Y S G S N G S R Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24432 972 102538 S204 H P T A A H H S P S T G A A A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q19691 423 46979
Sea Urchin Strong. purpuratus XP_791266 946 105128 S253 T D D K L S T S A N H N Q I Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 80 96.5 N.A. 87.5 81.6 N.A. 25.6 52.4 62.1 57.5 N.A. 22.9 N.A. 24.7 23.6
Protein Similarity: 100 99.1 82.9 96.9 N.A. 89.3 83.9 N.A. 33.5 54.5 70.5 68.9 N.A. 35.2 N.A. 34.9 37.9
P-Site Identity: 100 100 93.3 100 N.A. 93.3 0 N.A. 0 0 13.3 13.3 N.A. 6.6 N.A. 0 6.6
P-Site Similarity: 100 100 93.3 100 N.A. 93.3 13.3 N.A. 0 0 13.3 26.6 N.A. 26.6 N.A. 0 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 16 8 8 0 0 0 8 0 0 0 16 16 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 8 39 0 0 0 16 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 39 0 0 0 8 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 0 8 0 0 0 0 16 0 0 16 0 0 0 % G
% His: 8 0 0 0 0 8 8 0 0 0 8 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % I
% Lys: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 8 39 8 0 0 8 8 0 39 0 0 % L
% Met: 0 0 39 0 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 8 8 8 0 0 0 % N
% Pro: 0 8 0 8 0 0 0 0 8 0 0 0 0 16 0 % P
% Gln: 0 8 0 0 0 0 0 0 0 0 0 8 8 24 8 % Q
% Arg: 0 0 0 8 8 0 0 0 0 39 0 0 0 16 0 % R
% Ser: 0 47 0 0 47 16 39 62 8 24 8 8 8 0 47 % S
% Thr: 16 8 16 0 0 0 8 0 0 0 8 0 0 0 0 % T
% Val: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 39 0 0 0 8 8 8 0 0 0 39 39 0 0 16 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _